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2D UNet3+ Pytorch实现 脑肿瘤分割

程序员文章站 2022-07-05 11:05:33
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一、网络介绍

论文下载地址及论文翻译与解读:

玖零猴:UNet3+(UNet+++)论文翻译与详细解读

原代码链接: 链接

二、BraTs数据预处理

本文用的训练集和验证集均来自BraTs2018的训练集(其中HGG:210个病人,LGG:75个病人)

但由于BraTs只公开训练集数据,没有测试集数据,如果在训练集中再拆一部分用来作测试集的话,那训练集便少了许多,训练数据如果过少,容易出现过拟合现象,即在训练集中表现好,而在测试集中表现差,此时的网络泛化能力变差了.为了解决数据少的问题,灵机一动的我想出了一个办法.

因为BraTs2019的训练集在BraTs2018的基础上增多了,其中HGG增加了49例,LGG增加了1例,那么我就把这些新增的作为我的测试集

下面我提供百度云盘给大家下载,这是原始数据

        BraTs18数据集下载地址(不包含测试集,提供的验证集无GT) 
链接:https://pan.baidu.com/s/1Ry41OVl9VLOMzhQQR9qXuA 提取码:qvmo
BraTs19数据集下载地址如下(不包含测试集,提供的验证集无GT) 
链接: https://pan.baidu.com/s/1S5XGTdHkwFnagKS-5vWYBg 提取码: 2333
      

数据的预处理以及实现代码

把上面两年的数据下下来,然后我对数据的预处理方法是链接

完整的实现代码(jupyter notebook打开)

https://github.com/Merofine/BraTS2Dpreprocessing
  1. GetTrainingSets.ipynb——>训练集和验证集
  2. GetTestingSetsFrom2019.ipynb-—>测试集

代码执行完后,获得npy数据

2D UNet3+ Pytorch实现 脑肿瘤分割

<如果大家嫌麻烦,我这里提供预处理好的npy数据>

        链接:https://pan.baidu.com/s/1W3rcl9I-Y8DwWu5p4o--cw  密码:hfe7
      

三、运行环境的安装

1、系统环境 WIN10 + CUDA 92 + CUDNN7 + ANACONDA

2、ANACONDA指令快速配置环境,先下载下面文件

https://download.csdn.net/downl

2D UNet3+ Pytorch实现 脑肿瘤分割

四、核心代码

        # -*- coding: utf-8 -*-
import torch
import torch.nn as nn
import torch.nn.functional as F
from layers import unetConv2
from init_weights import init_weights
'''
    UNet 3+
'''
class UNet_3Plus(nn.Module):

    def __init__(self, args):
        super(UNet_3Plus, self).__init__()
        self.args = args
        in_channels = 4
        n_classes = 3
        feature_scale = 4
        is_deconv = True
        is_batchnorm = True
        self.is_deconv = is_deconv
        self.in_channels = in_channels
        self.is_batchnorm = is_batchnorm
        self.feature_scale = feature_scale

        filters = [64, 128, 256, 512, 1024]

        ## -------------Encoder--------------
        self.conv1 = unetConv2(self.in_channels, filters[0], self.is_batchnorm)
        self.maxpool1 = nn.MaxPool2d(kernel_size=2)

        self.conv2 = unetConv2(filters[0], filters[1], self.is_batchnorm)
        self.maxpool2 = nn.MaxPool2d(kernel_size=2)

        self.conv3 = unetConv2(filters[1], filters[2], self.is_batchnorm)
        self.maxpool3 = nn.MaxPool2d(kernel_size=2)

        self.conv4 = unetConv2(filters[2], filters[3], self.is_batchnorm)
        self.maxpool4 = nn.MaxPool2d(kernel_size=2)

        self.conv5 = unetConv2(filters[3], filters[4], self.is_batchnorm)

        ## -------------Decoder--------------
        self.CatChannels = filters[0]
        self.CatBlocks = 5
        self.UpChannels = self.CatChannels * self.CatBlocks

        '''stage 4d'''
        # h1->320*320, hd4->40*40, Pooling 8 times
        self.h1_PT_hd4 = nn.MaxPool2d(8, 8, ceil_mode=True)
        self.h1_PT_hd4_conv = nn.Conv2d(filters[0], self.CatChannels, 3, padding=1)
        self.h1_PT_hd4_bn = nn.BatchNorm2d(self.CatChannels)
        self.h1_PT_hd4_relu = nn.ReLU(inplace=True)

        # h2->160*160, hd4->40*40, Pooling 4 times
        self.h2_PT_hd4 = nn.MaxPool2d(4, 4, ceil_mode=True)
        self.h2_PT_hd4_conv = nn.Conv2d(filters[1], self.CatChannels, 3, padding=1)
        self.h2_PT_hd4_bn = nn.BatchNorm2d(self.CatChannels)
        self.h2_PT_hd4_relu = nn.ReLU(inplace=True)

        # h3->80*80, hd4->40*40, Pooling 2 times
        self.h3_PT_hd4 = nn.MaxPool2d(2, 2, ceil_mode=True)
        self.h3_PT_hd4_conv = nn.Conv2d(filters[2], self.CatChannels, 3, padding=1)
        self.h3_PT_hd4_bn = nn.BatchNorm2d(self.CatChannels)
        self.h3_PT_hd4_relu = nn.ReLU(inplace=True)

        # h4->40*40, hd4->40*40, Concatenation
        self.h4_Cat_hd4_conv = nn.Conv2d(filters[3], self.CatChannels, 3, padding=1)
        self.h4_Cat_hd4_bn = nn.BatchNorm2d(self.CatChannels)
        self.h4_Cat_hd4_relu = nn.ReLU(inplace=True)

        # hd5->20*20, hd4->40*40, Upsample 2 times
        self.hd5_UT_hd4 = nn.Upsample(scale_factor=2, mode='bilinear')  # 14*14
        self.hd5_UT_hd4_conv = nn.Conv2d(filters[4], self.CatChannels, 3, padding=1)
        self.hd5_UT_hd4_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd5_UT_hd4_relu = nn.ReLU(inplace=True)

        # fusion(h1_PT_hd4, h2_PT_hd4, h3_PT_hd4, h4_Cat_hd4, hd5_UT_hd4)
        self.conv4d_1 = nn.Conv2d(self.UpChannels, self.UpChannels, 3, padding=1)  # 16
        self.bn4d_1 = nn.BatchNorm2d(self.UpChannels)
        self.relu4d_1 = nn.ReLU(inplace=True)

        '''stage 3d'''
        # h1->320*320, hd3->80*80, Pooling 4 times
        self.h1_PT_hd3 = nn.MaxPool2d(4, 4, ceil_mode=True)
        self.h1_PT_hd3_conv = nn.Conv2d(filters[0], self.CatChannels, 3, padding=1)
        self.h1_PT_hd3_bn = nn.BatchNorm2d(self.CatChannels)
        self.h1_PT_hd3_relu = nn.ReLU(inplace=True)

        # h2->160*160, hd3->80*80, Pooling 2 times
        self.h2_PT_hd3 = nn.MaxPool2d(2, 2, ceil_mode=True)
        self.h2_PT_hd3_conv = nn.Conv2d(filters[1], self.CatChannels, 3, padding=1)
        self.h2_PT_hd3_bn = nn.BatchNorm2d(self.CatChannels)
        self.h2_PT_hd3_relu = nn.ReLU(inplace=True)

        # h3->80*80, hd3->80*80, Concatenation
        self.h3_Cat_hd3_conv = nn.Conv2d(filters[2], self.CatChannels, 3, padding=1)
        self.h3_Cat_hd3_bn = nn.BatchNorm2d(self.CatChannels)
        self.h3_Cat_hd3_relu = nn.ReLU(inplace=True)

        # hd4->40*40, hd4->80*80, Upsample 2 times
        self.hd4_UT_hd3 = nn.Upsample(scale_factor=2, mode='bilinear')  # 14*14
        self.hd4_UT_hd3_conv = nn.Conv2d(self.UpChannels, self.CatChannels, 3, padding=1)
        self.hd4_UT_hd3_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd4_UT_hd3_relu = nn.ReLU(inplace=True)

        # hd5->20*20, hd4->80*80, Upsample 4 times
        self.hd5_UT_hd3 = nn.Upsample(scale_factor=4, mode='bilinear')  # 14*14
        self.hd5_UT_hd3_conv = nn.Conv2d(filters[4], self.CatChannels, 3, padding=1)
        self.hd5_UT_hd3_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd5_UT_hd3_relu = nn.ReLU(inplace=True)

        # fusion(h1_PT_hd3, h2_PT_hd3, h3_Cat_hd3, hd4_UT_hd3, hd5_UT_hd3)
        self.conv3d_1 = nn.Conv2d(self.UpChannels, self.UpChannels, 3, padding=1)  # 16
        self.bn3d_1 = nn.BatchNorm2d(self.UpChannels)
        self.relu3d_1 = nn.ReLU(inplace=True)

        '''stage 2d '''
        # h1->320*320, hd2->160*160, Pooling 2 times
        self.h1_PT_hd2 = nn.MaxPool2d(2, 2, ceil_mode=True)
        self.h1_PT_hd2_conv = nn.Conv2d(filters[0], self.CatChannels, 3, padding=1)
        self.h1_PT_hd2_bn = nn.BatchNorm2d(self.CatChannels)
        self.h1_PT_hd2_relu = nn.ReLU(inplace=True)

        # h2->160*160, hd2->160*160, Concatenation
        self.h2_Cat_hd2_conv = nn.Conv2d(filters[1], self.CatChannels, 3, padding=1)
        self.h2_Cat_hd2_bn = nn.BatchNorm2d(self.CatChannels)
        self.h2_Cat_hd2_relu = nn.ReLU(inplace=True)

        # hd3->80*80, hd2->160*160, Upsample 2 times
        self.hd3_UT_hd2 = nn.Upsample(scale_factor=2, mode='bilinear')  # 14*14
        self.hd3_UT_hd2_conv = nn.Conv2d(self.UpChannels, self.CatChannels, 3, padding=1)
        self.hd3_UT_hd2_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd3_UT_hd2_relu = nn.ReLU(inplace=True)

        # hd4->40*40, hd2->160*160, Upsample 4 times
        self.hd4_UT_hd2 = nn.Upsample(scale_factor=4, mode='bilinear')  # 14*14
        self.hd4_UT_hd2_conv = nn.Conv2d(self.UpChannels, self.CatChannels, 3, padding=1)
        self.hd4_UT_hd2_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd4_UT_hd2_relu = nn.ReLU(inplace=True)

        # hd5->20*20, hd2->160*160, Upsample 8 times
        self.hd5_UT_hd2 = nn.Upsample(scale_factor=8, mode='bilinear')  # 14*14
        self.hd5_UT_hd2_conv = nn.Conv2d(filters[4], self.CatChannels, 3, padding=1)
        self.hd5_UT_hd2_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd5_UT_hd2_relu = nn.ReLU(inplace=True)

        # fusion(h1_PT_hd2, h2_Cat_hd2, hd3_UT_hd2, hd4_UT_hd2, hd5_UT_hd2)
        self.conv2d_1 = nn.Conv2d(self.UpChannels, self.UpChannels, 3, padding=1)  # 16
        self.bn2d_1 = nn.BatchNorm2d(self.UpChannels)
        self.relu2d_1 = nn.ReLU(inplace=True)

        '''stage 1d'''
        # h1->320*320, hd1->320*320, Concatenation
        self.h1_Cat_hd1_conv = nn.Conv2d(filters[0], self.CatChannels, 3, padding=1)
        self.h1_Cat_hd1_bn = nn.BatchNorm2d(self.CatChannels)
        self.h1_Cat_hd1_relu = nn.ReLU(inplace=True)

        # hd2->160*160, hd1->320*320, Upsample 2 times
        self.hd2_UT_hd1 = nn.Upsample(scale_factor=2, mode='bilinear')  # 14*14
        self.hd2_UT_hd1_conv = nn.Conv2d(self.UpChannels, self.CatChannels, 3, padding=1)
        self.hd2_UT_hd1_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd2_UT_hd1_relu = nn.ReLU(inplace=True)

        # hd3->80*80, hd1->320*320, Upsample 4 times
        self.hd3_UT_hd1 = nn.Upsample(scale_factor=4, mode='bilinear')  # 14*14
        self.hd3_UT_hd1_conv = nn.Conv2d(self.UpChannels, self.CatChannels, 3, padding=1)
        self.hd3_UT_hd1_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd3_UT_hd1_relu = nn.ReLU(inplace=True)

        # hd4->40*40, hd1->320*320, Upsample 8 times
        self.hd4_UT_hd1 = nn.Upsample(scale_factor=8, mode='bilinear')  # 14*14
        self.hd4_UT_hd1_conv = nn.Conv2d(self.UpChannels, self.CatChannels, 3, padding=1)
        self.hd4_UT_hd1_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd4_UT_hd1_relu = nn.ReLU(inplace=True)

        # hd5->20*20, hd1->320*320, Upsample 16 times
        self.hd5_UT_hd1 = nn.Upsample(scale_factor=16, mode='bilinear')  # 14*14
        self.hd5_UT_hd1_conv = nn.Conv2d(filters[4], self.CatChannels, 3, padding=1)
        self.hd5_UT_hd1_bn = nn.BatchNorm2d(self.CatChannels)
        self.hd5_UT_hd1_relu = nn.ReLU(inplace=True)

        # fusion(h1_Cat_hd1, hd2_UT_hd1, hd3_UT_hd1, hd4_UT_hd1, hd5_UT_hd1)
        self.conv1d_1 = nn.Conv2d(self.UpChannels, self.UpChannels, 3, padding=1)  # 16
        self.bn1d_1 = nn.BatchNorm2d(self.UpChannels)
        self.relu1d_1 = nn.ReLU(inplace=True)

        # output
        self.outconv1 = nn.Conv2d(self.UpChannels, n_classes, 3, padding=1)

        # initialise weights
        for m in self.modules():
            if isinstance(m, nn.Conv2d):
                init_weights(m, init_type='kaiming')
            elif isinstance(m, nn.BatchNorm2d):
                init_weights(m, init_type='kaiming')

    def forward(self, inputs):
        ## -------------Encoder-------------
        h1 = self.conv1(inputs)  # h1->320*320*64

        h2 = self.maxpool1(h1)
        h2 = self.conv2(h2)  # h2->160*160*128

        h3 = self.maxpool2(h2)
        h3 = self.conv3(h3)  # h3->80*80*256

        h4 = self.maxpool3(h3)
        h4 = self.conv4(h4)  # h4->40*40*512

        h5 = self.maxpool4(h4)
        hd5 = self.conv5(h5)  # h5->20*20*1024

        ## -------------Decoder-------------
        h1_PT_hd4 = self.h1_PT_hd4_relu(self.h1_PT_hd4_bn(self.h1_PT_hd4_conv(self.h1_PT_hd4(h1))))
        h2_PT_hd4 = self.h2_PT_hd4_relu(self.h2_PT_hd4_bn(self.h2_PT_hd4_conv(self.h2_PT_hd4(h2))))
        h3_PT_hd4 = self.h3_PT_hd4_relu(self.h3_PT_hd4_bn(self.h3_PT_hd4_conv(self.h3_PT_hd4(h3))))
        h4_Cat_hd4 = self.h4_Cat_hd4_relu(self.h4_Cat_hd4_bn(self.h4_Cat_hd4_conv(h4)))
        hd5_UT_hd4 = self.hd5_UT_hd4_relu(self.hd5_UT_hd4_bn(self.hd5_UT_hd4_conv(self.hd5_UT_hd4(hd5))))
        hd4 = self.relu4d_1(self.bn4d_1(self.conv4d_1(
            torch.cat((h1_PT_hd4, h2_PT_hd4, h3_PT_hd4, h4_Cat_hd4, hd5_UT_hd4), 1)))) # hd4->40*40*UpChannels

        h1_PT_hd3 = self.h1_PT_hd3_relu(self.h1_PT_hd3_bn(self.h1_PT_hd3_conv(self.h1_PT_hd3(h1))))
        h2_PT_hd3 = self.h2_PT_hd3_relu(self.h2_PT_hd3_bn(self.h2_PT_hd3_conv(self.h2_PT_hd3(h2))))
        h3_Cat_hd3 = self.h3_Cat_hd3_relu(self.h3_Cat_hd3_bn(self.h3_Cat_hd3_conv(h3)))
        hd4_UT_hd3 = self.hd4_UT_hd3_relu(self.hd4_UT_hd3_bn(self.hd4_UT_hd3_conv(self.hd4_UT_hd3(hd4))))
        hd5_UT_hd3 = self.hd5_UT_hd3_relu(self.hd5_UT_hd3_bn(self.hd5_UT_hd3_conv(self.hd5_UT_hd3(hd5))))
        hd3 = self.relu3d_1(self.bn3d_1(self.conv3d_1(
            torch.cat((h1_PT_hd3, h2_PT_hd3, h3_Cat_hd3, hd4_UT_hd3, hd5_UT_hd3), 1)))) # hd3->80*80*UpChannels

        h1_PT_hd2 = self.h1_PT_hd2_relu(self.h1_PT_hd2_bn(self.h1_PT_hd2_conv(self.h1_PT_hd2(h1))))
        h2_Cat_hd2 = self.h2_Cat_hd2_relu(self.h2_Cat_hd2_bn(self.h2_Cat_hd2_conv(h2)))
        hd3_UT_hd2 = self.hd3_UT_hd2_relu(self.hd3_UT_hd2_bn(self.hd3_UT_hd2_conv(self.hd3_UT_hd2(hd3))))
        hd4_UT_hd2 = self.hd4_UT_hd2_relu(self.hd4_UT_hd2_bn(self.hd4_UT_hd2_conv(self.hd4_UT_hd2(hd4))))
        hd5_UT_hd2 = self.hd5_UT_hd2_relu(self.hd5_UT_hd2_bn(self.hd5_UT_hd2_conv(self.hd5_UT_hd2(hd5))))
        hd2 = self.relu2d_1(self.bn2d_1(self.conv2d_1(
            torch.cat((h1_PT_hd2, h2_Cat_hd2, hd3_UT_hd2, hd4_UT_hd2, hd5_UT_hd2), 1)))) # hd2->160*160*UpChannels

        h1_Cat_hd1 = self.h1_Cat_hd1_relu(self.h1_Cat_hd1_bn(self.h1_Cat_hd1_conv(h1)))
        hd2_UT_hd1 = self.hd2_UT_hd1_relu(self.hd2_UT_hd1_bn(self.hd2_UT_hd1_conv(self.hd2_UT_hd1(hd2))))
        hd3_UT_hd1 = self.hd3_UT_hd1_relu(self.hd3_UT_hd1_bn(self.hd3_UT_hd1_conv(self.hd3_UT_hd1(hd3))))
        hd4_UT_hd1 = self.hd4_UT_hd1_relu(self.hd4_UT_hd1_bn(self.hd4_UT_hd1_conv(self.hd4_UT_hd1(hd4))))
        hd5_UT_hd1 = self.hd5_UT_hd1_relu(self.hd5_UT_hd1_bn(self.hd5_UT_hd1_conv(self.hd5_UT_hd1(hd5))))
        hd1 = self.relu1d_1(self.bn1d_1(self.conv1d_1(
            torch.cat((h1_Cat_hd1, hd2_UT_hd1, hd3_UT_hd1, hd4_UT_hd1, hd5_UT_hd1), 1)))) # hd1->320*320*UpChannels

        d1 = self.outconv1(hd1)  # d1->320*320*n_classes
        return d1
      

完整代码请私聊博主~(QQ:704783475)

五、训练

        python train.py --arch=“unet3d” --dataset=“Jiu0Monkey”
      

六、测试

        python test.py --name="jiu0Monkey_unet3d_woDS"
      

七、与其它模型对比

2D UNet3+ Pytorch实现 脑肿瘤分割